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Because macros can contain viruses, be careful about running them. Take the following precautions: run up-to-date antivirus software on your computer; set your macro security level to high; clear the Trust all installed add-ins and templates check box; use digital signatures; maintain a list of trusted publishers.
If you want to run a macro when you hover the pointer over the button, object, or drawing object, on the Mouse Over tab, click Run macro, and then select the macro you want to run from the list.
If the new object isn't selected, select it again, click AutoShape on the Format menu, and then click the Color and Lines tab.
In the Color box under Fill, click No Fill, and then in the Color box under Line, click No Line.
Repeat these steps for each hot spot you want to create.